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NeoStrep

Development of Group B Streptococcal vaccine

NeoStrep is funded by the European Commission FP7 Programme HEALTH


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WORK PACKAGE 1

WP1 will perform dose-finding experiments with GBS-NN for studies of antibody levels, isotyping and longevity of antibody response as well as testing of optimal adjuvant-antigen compositions.



Objectives


Understand the expected dose and dosing regimen in preparation for toxicology and clinical trials as well as to identify the mechanism of action of anti-GBS-NN antibodies.


The specific objectives are: